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Ganglioblockers are used in the combined therapy of pulmonary and cerebral edema, are used in surgical interventions, during operations on the brain, heart.
As a result of the upcoming drop in blood pressure (hypotension), the possibility of bleeding decreases, which facilitates the operation. In anesthesiology, fractional administration of ganglioblockers can lower blood pressure to the desired level, thus achieving controlled or controlled hypotension. In this case, the average blood pressure should not be lower than 60-70 mm Hg, otherwise collapse, anemia of the brain are possible.
In case of an overdose of agents, it is recommended to introduce peripheral vasoconstrictors: ephedrine, phenylephrine, norepinephrine.
Allergic reactions to the constituent components of the drug are possible. sodium oxybutiratis twenty% — ten ml Table 7 Dosage and administration 1288.
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In case of insufficient effect, the dose of the drug is increased to 4 capsules per day.
Treatment should be continued until the desired therapeutic effect is achieved. With the / m administration, repeated administration of the drug in the same place should be avoided. The usual maintenance dose is 10-20 mg per day, the maximum dose should not exceed 20 mg 2 times a day. As well as various combination drugs this groups, for example "Pantogen" (pantocrine + zhen- shen + vitamins groups b) and others Bradycardia, extrasystole, bigeminia, dissociation of the heart rhythm, impaired conduction function, as well as nausea, vomiting, abdominal pain, diarrhea, and impaired color vision may occur. Intravenously drip, The main causes of atherosclerosis are elevated plasma levels of atherogenic lipoproteins (LDL, VLDL), increased permeability of the endothelial vascular wall, and impaired lipid metabolism. A significant role in the pathogenesis of atherosclerosis is played by modified LDL, which are absorbed by phagocytic macrophages with the formation of foam cells capable of accumulating high concentrations of free cholesterol.
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When taking the drug for 4 weeks, a lasting effect of treatment is achieved.
Contraindications tonic agents (adaptogens) have a general effect . Anesthesia or general anesthetics (halothane, sodium hydroxybutyrate) have a general reversible inhibitory effect on CNS cells.
The drug is usually well tolerated by patients, extremely rarely
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