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The lack of indications of higher doses for a number of drugs can be explained by the fact that either such a dose has not yet been legally established for one reason or another, or by the fact that the drug has low toxicity and the risk of using such doses is not very high. In any case, the indication of the highest dose is valid only if the route of administration is indicated simultaneously. Currently, due to toxicity, they are mainly used topically for dermatomycosis and superficial candidomycosis.

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