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Interleukin-1 (IL-1) stimulates endogenous pyrogen and bone marrow cell growth, and is an inflammatory mediator.

Many ILs activate the inflammatory process; first of all, IL-1 is released by expressed macrophages.

IL-1 is perceived by receptors on the surface of many cells, as a result, the synthesis of antibodies is enhanced, a cascade of production of IL-2, IL-3, IL-4, IL-5, etc.

That is why IL-1 is considered an antitumor and hyperthermic cytokine.

Interleukin-2 (IL-2) stimulates the proliferation of T cells and their activation into "killer cells".

Interleukin-3 (IL3) stimulates early precursors in the bone marrow; "multi-CSF" Interleukin-4 (IL-4) stimulates the proliferation of antigen-activated B and T cells. Interleukin-5 (IL-5) stimulates the proliferation of eosinophils. Interleukin-6 (IL-6) stimulates plasma cells and early bone marrow precursors.

Interleukin-7 (IL-7) stimulates the proliferation and differentiation of early cell precursors. Interleukin-8 (IL-8) is a neutrophil chemotaxis factor. Interleukin-10 (IL-10) causes suppression of the immune response.

Interleukin-11 (IL-11) causes the proliferation of megakaryocytes and stimulates the differentiation of B-lymphocytes.

At present, with the help of genetic engineering and the use of E.

coli , many ILs have been obtained, the most famous drugs are the recombinant drug interleukin-2, proleukin ?

Recombinant human IL-11 is produced under the trade names Oprelvekin ¤ and Nyumega ? recipes With inscription "To apply compresses" (indicating the required concentration) or “For leather processing"; mixed with other ingredients at individual manufacturing medicines — not bo- more fifty G, a sick With chronic flow disease — before 100 G on recipes With inscription "By special on the- meaning”, separately signed by the doctor and seal treatment and prophylactic institutions.

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In pregnant women, use only under medical supervision.

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Leeches do not tolerate cold well, so in cold weather they are kept in a warm place.

Before use, in order to avoid the introduction of infection, it is necessary to thoroughly clean their proboscis.

Each leech sucks 5-7 ml of blood; usually put 2-4 leeches at the same time. A pressure bandage is applied to stop subsequent bleeding.

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