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With normal renal function, T 1/2 for erythromycin is 2-3 hours, for clarithromycin 5-7 hours, 10-20 hours for roxithromycin, and for azithromycin more than 48 hours. Macrolides are used to treat infections of the upper and lower respiratory tract (pneumonia, bronchitis, pharyngitis, acute sinusitis), diphtheria, scarlet fever, whooping cough, otitis media, infections of the skin, soft tissues, pelvic organs, oral cavity, sexually transmitted infections, and eradication of Helicobacter pylori in peptic ulcer, for the purpose of year-round prevention of rheumatism .

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Do not apply to open wounds, mucous membranes, the area of the purulent process.

For adults, the dose at the start of treatment should be 2060 mg and should be titrated according to thyroid function until the patient is euthyroid to reduce the risk of overtreatment and consequent hypothyroidism.

As part of complex therapy for varicose veins with edematous and pain syndromes, superficial thrombophlebitis, trophic disorders and ulcers, with chronic venous insufficiency, with hemorrhagic diathesis. Pharmakinase, Actilyse, Fibrinolysin, Metalise, Elaksim, Distreptase, Biostrepta, Urokinase Medak.

Thick, durable fabric used as operating towels and napkins.

Rational prevention of caries in children should begin from infancy and continue throughout the entire period of eruption of milk and permanent teeth.

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