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Kharkevich are devoted to various problems of neuropharmacology.

Particularly significant are his works in the field of pharmacology of autonomic ganglia and neuromuscular synapses.

He has published more than 250 scientific papers, including 12 monographs and textbooks. Kharkevich is the president of the Russian Scientific Society of Pharmacologists (1991), the editor-in-chief of the journal "Experimental and Clinical Pharmacology" (1988), a member of the editorial boards of a number of foreign publications. Sechenov, works at the Department of Pharmacology of the Medical and Preventive Medicine Faculties. Gestonoroni caproas Contraindications For prevention candidiasis appoint inside 25,000–30,000 U/kg per day. When the mushroom colic infection, doses are used that are 2–2.5 times higher than shaking preventive. Group Psychogenic neuroses (hysteria, neurasthenia, obsessive-compulsive disorder), accompanied by irritability, bad mood, insomnia, can develop as a result of abnormally increased excitability of brain cells or as a result of a weakening of inhibitory processes in them. Silver compounds are characterized by significantly pronounced antimicrobial properties, especially in relation to the coccal group of bacteria. In low concentrations, it has an astringent and anti-inflammatory effect.

The effect of strong solutions (1% and above) of silver nitrate on tissues is

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. Interacting with proteins, silver nitrate forms a dense albuminate, which gradually acquires a black color, which is associated with the reduction of silver. Silver nitrate is used in surgery for the treatment of wounds (a cauterizing agent in case of excessive damage to granulation tissue), eye practice: in case of blenorrhea (purulent eye damage), newborns are instilled 1 drop of a 2% solution in each eye, followed by washing with isotonic sodium chloride solution.

Sometimes it is prescribed orally for peptic ulcer.

A colloidal solution of silver proteinate (protargol ? The drug is used as an antiseptic and anti-inflammatory agent. 1-3% (silver albuminate with a content of 8% silver) irrigates the mucous membranes with blepharitis, blenorrhea, urethritis.

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Contraindications Sometimes hypersensitivity reactions may occur in the form of redness, slight burning, itching of the

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    Associated esophagitis usually takes 4 to 8 weeks to heal. Immediately after a significant oral overdose, gastric lavage or induction of vomiting should be considered. Lymphogranulomatosis; myeloid leukemia; chronic lymphocytic leukemia. gallstone disease Arterial hypotension, hypovolemia, shock, myocardial pathology, thrombosis, glaucoma, impaired liver and kidney function, CNS diseases. Contraindications Symptomatic treatment of constipation.

    Pharmachologic effect Depending on the chemical structure, azoles are distinguished: imidazole derivatives - clotrimazole, miconazole, ketoconazole, butoconazole; triazole derivatives - fluconazole, itraconazole, voriconazole (Vfend ? ); allylamines (derivatives of N-methylnaphthalene) - terbinafine, naftifine (exoderil ?

    ) and various chemical groups - undecylenic acid (mykoseptin ? Azole drugs inhibit key enzymes in the biosynthesis of ergosterol, the main structural component of the fungal membrane. Inhibition of cytochrome P-450-dependent one List B Appoint inside.

    children preschool age — on 1 / 2 tab., schoolchildren on one tab. 3–4 times in day Tablet- it is desirable to dissolve ku in 1/3 cup of water, you can add sugar syrup and to give drink before food.

    Previously, drugs were obtained mainly from the glands of cattle and pigs. In 1980, human insulin was invented using genetic engineering methods. By the biosynthetic method, human insulin preparations are obtained from cultures of Escherichia coli and yeast cells: Actrapid NM ? When prescribing human insulins, one should take into account the important fact that they are 20-25% more active than animal insulins. Technologies have been created for a special multi-stage purification of insulin using ion-exchange chromatography to remove high-molecular protein impurities that have strong antigenic properties and cause allergic reactions.

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