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Children over 10 years old: 1 tablet 2 times a day. Elderly people do not need to adjust the dosing regimen.
sodium entering the cardiomyocyte in the depolarization phase, thus delaying the entry of potassium into the cell.
An increase in the concentration of sodium in the cell activates the sodium-calcium mechanism on the outer membrane (Na + -Ca 2+ -antiport), which enhances the entry of calcium into myocardiocytes and increases the release of calcium from the cisterns of the sarcoplasmic reticulum (in the depot, Ca 2+ is associated with the protein calsequestrin), as Buy Isoptin Sr (Verapamil) 120mg, 240mg online - Blood Pressure well as from mitochondria, where it accumulates during diastole. An increase in free calcium ions in the cytoplasm promotes their interaction with the ATP-tropomyosin complex. The inhibitory effect on the other two contractile proteins actin and myosin is eliminated; the rate of interaction of transverse myosin bridges with the actin filament increases, contributing to the formation of actomyosin.
The greater the number of calcium ions,
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In this case, it is necessary to stop using the drug.
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Reduces the viscosity of sputum, increases the evacuation of mucus. Dragee Antiatherosclerotic (lipipidemic) agents are those that reduce the content of atherogenic lipoproteins in the blood and are used for the prevention and treatment of atherosclerosis and its complications. intravenous infusion (before 200 ml one-time calling). Significantly more often, subcutaneous and intramuscular methods of drug administration are used, which provide a relatively accurate dosage and rapid entry of drugs into the general bloodstream.
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