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Adults take orally 15-20 minutes before meals 1 tablet 2-3 times a day. The duration of the course of treatment depends on the severity of the disease and can range from 1 to 2 months.
(registered in 1957); ?-glycosidase inhibitors (1995); clays; thiazolidinediones (glitazones) entered clinical practice in 1997; glucagon-like peptide-I agonists; amylin agonists (2005); type IV dipeptidyl peptidase inhibitors (2006).
Synthetic hypoglycemic agents are used orally to correct disorders, reduce symptoms and stop further progression of the disease, to treat non-insulin-dependent diabetes mellitus in elderly patients and to reduce the daily dose of insulin in the complex treatment of type 1 diabetes mellitus.
Unlike insulin preparations, they are not replacement therapy preparations.
In juvenile diabetes, when the cells of the pancreatic islets are destroyed, they are ineffective. Recently, drugs have appeared that affect the production and activity of incretins. Hormones of the incretin family are secreted in the intestine, participate in the regulation of glucose homeostasis, increase the synthesis of insulin by ?-cells of the islets of Langerhans of the pancreas, suppress the secretion of glucagon, reduce the production of glucose by the liver, which leads to a decrease in glycemia. The most interesting developments
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Cholagogues are drugs that increase the secretion of bile and promote its release into the intestines. They are used in the treatment of hepatitis (inflammation of the liver tissue), cholelithiasis, cholecystitis (inflammation of the gallbladder) and other diseases of the liver and biliary tract.
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